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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732441
Species: Homo sapiens
RGD Object: Gene
Symbol: TXN
Name: thioredoxin
Acc ID: CHEBI:34718
Term: 1-chloro-2,4-dinitrobenzene
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Chemical ID: MESH:D004137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TXNincreases oxidationEXP 6480464CTDDinitrochlorobenzene results in increased oxidation of TXN proteinPMID:26975474
TXNmultiple interactionsEXP 6480464CTDDinitrochlorobenzene inhibits the reaction [Selegiline results in increased expression of TXN]; Dinitrochlorobenzene inhibits the reaction [TXN protein affects the susceptibility to Selegiline]PMID:16099847
TXNincreases expressionISOTxn1 (Mus musculus)6480464CTDDinitrochlorobenzene results in increased expression of TXN1 mRNAPMID:19647056
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