Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69659
Species: Homo sapiens
RGD Object: Gene
Symbol: ICAM1
Name: intercellular adhesion molecule 1
Acc ID: CHEBI:34718
Term: 1-chloro-2,4-dinitrobenzene
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Chemical ID: MESH:D004137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ICAM1affects expressionEXP 6480464CTDDinitrochlorobenzene affects the expression of ICAM1 proteinPMID:30842373
ICAM1increases expressionEXP 6480464CTDDinitrochlorobenzene results in increased expression of ICAM1 mRNA; Dinitrochlorobenzene results in increased expression of ICAM1 proteinPMID:15737199 PMID:19427879 PMID:20417223 PMID:21742781 PMID:29743441 PMID:33774146
ICAM1multiple interactionsEXP 6480464CTDAcetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]; cariporide inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Citric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Lactic Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Potassium Chloride affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]PMID:29743441 PMID:30842373
Go Back to source page   Continue to Ontology report