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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349768
Species: Homo sapiens
RGD Object: Gene
Symbol: GSTM3
Name: glutathione S-transferase mu 3
Acc ID: CHEBI:34718
Term: 1-chloro-2,4-dinitrobenzene
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Chemical ID: MESH:D004137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSTM3affects metabolic processingEXP 6480464CTDGSTM3 protein affects the metabolism of DinitrochlorobenzenePMID:9545290
GSTM3decreases metabolic processingEXP 6480464CTDGSTM3 protein polymorphism results in decreased metabolism of DinitrochlorobenzenePMID:15247628
GSTM3increases metabolic processingEXP 6480464CTDGSTM3 protein polymorphism results in increased metabolism of DinitrochlorobenzenePMID:15247628
GSTM3affects metabolic processingISOGstm5 (Rattus norvegicus)6480464CTDGSTM3 protein affects the metabolism of DinitrochlorobenzenePMID:3169012
GSTM3decreases expressionISOGstm5 (Mus musculus)6480464CTDDinitrochlorobenzene results in decreased expression of GSTM3 mRNAPMID:21404309
GSTM3increases expressionISOGstm5 (Rattus norvegicus)6480464CTDDinitrochlorobenzene results in increased expression of GSTM3 proteinPMID:9794801
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