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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70373
Species: Homo sapiens
RGD Object: Gene
Symbol: BAX
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:34698
Term: diethyl phthalate
Definition: The diethyl ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C007379
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BAXincreases expressionISOBax (Mus musculus)6480464CTDdiethyl phthalate results in increased expression of BAX proteinPMID:37942807
BAXmultiple interactionsISOBax (Mus musculus)6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of BAX protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of BAX protein; [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with Diethylhexyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in increased expression of BAX mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of BAX mRNAPMID:28013214 PMID:35739755 PMID:37021957 PMID:37364641
BAXmultiple interactionsISOBax (Rattus norvegicus)6480464CTD[bisphenol S co-treated with diethyl phthalate] results in increased expression of BAX mRNA; morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased expression of BAX mRNA]PMID:35900689
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