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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10439
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:34698
Term: diethyl phthalate
Definition: The diethyl ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C007379
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1increases expressionISOCYP1B1 (Homo sapiens)6480464CTDdiethyl phthalate results in increased expression of CYP1B1 mRNAPMID:16040568
Cyp1b1multiple interactionsISOCYP1B1 (Homo sapiens)6480464CTDdiethyl phthalate results in increased expression of and results in increased activity of CYP1B1 proteinPMID:16040568
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