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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736047
Species: Mus musculus
RGD Object: Gene
Symbol: Notch2
Name: notch 2
Acc ID: CHEBI:34696
Term: dieldrin
Definition: An organochlorine compound resulting from the epoxidation of the double bond of aldrin. It is the active metabolite of the proinsecticde aldrin.
Chemical ID: MESH:D004026
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Notch2affects expressionISONotch2 (Rattus norvegicus)6480464CTDDieldrin affects the expression of NOTCH2 mRNAPMID:22546817
Notch2decreases expressionISONOTCH2 (Homo sapiens)6480464CTDDieldrin results in decreased expression of NOTCH2 mRNAPMID:31068361
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