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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3403
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prl
Name: prolactin
Acc ID: CHEBI:34696
Term: dieldrin
Definition: An organochlorine compound resulting from the epoxidation of the double bond of aldrin. It is the active metabolite of the proinsecticde aldrin.
Chemical ID: MESH:D004026
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases secretionEXP 6480464CTDDieldrin results in increased secretion of PRL protein

PMID:15811834, PMID:17174995
multiple interactionsEXP 6480464CTDNifedipine inhibits the reaction [Dieldrin results in increased secretion of PRL protein]

PMID:15811834
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.