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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
Acc ID: CHEBI:34690
Term: dichlorvos
Definition: An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate.
Chemical ID: MESH:D004006
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1aincreases expressionEXP 6480464CTDDichlorvos results in increased expression of CDKN1A mRNA; Dichlorvos results in increased expression of CDKN1A proteinPMID:21813463 PMID:24369695
Cdkn1amultiple interactionsEXP 6480464CTDTEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A protein]PMID:24369695
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