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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319073
Species: Mus musculus
RGD Object: Gene
Symbol: Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Acc ID: CHEBI:34690
Term: dichlorvos
Definition: An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate.
Chemical ID: MESH:D004006
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkdcincreases expressionISOPrkdc (Rattus norvegicus)6480464CTDDichlorvos results in increased expression of PRKDC mRNA; Dichlorvos results in increased expression of PRKDC proteinPMID:24369695
Prkdcmultiple interactionsISOPrkdc (Rattus norvegicus)6480464CTDTEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of PRKDC mRNA]PMID:24369695
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