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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735634
Species: Mus musculus
RGD Object: Gene
Symbol: Scarb1
Name: scavenger receptor class B, member 1
Acc ID: CHEBI:34680
Term: dipentyl phthalate
Definition: A phthalate ester that is the dipentyl ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C034171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scarb1decreases expressionISOScarb1 (Rattus norvegicus)6480464CTDdi-n-pentyl phthalate results in decreased expression of SCARB1 mRNA; di-n-pentyl phthalate results in decreased expression of SCARB1 proteinPMID:19560483 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 PMID:33983380 PMID:36715143
Scarb1multiple interactionsISOScarb1 (Rattus norvegicus)6480464CTD[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SCARB1 mRNAPMID:25055962
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