GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CNR2 | affects response to substance | ISO | Cnr2 (Mus musculus) | 6480464 | CTD | CNR2 protein affects the susceptibility to Dextran Sulfate | PMID:27611972 | CNR2 | increases expression | ISO | Cnr2 (Mus musculus) | 6480464 | CTD | Dextran Sulfate results in increased expression of CNR2 protein | PMID:27920472 | CNR2 | increases response to substance | ISO | Cnr2 (Mus musculus) | 6480464 | CTD | CNR2 gene mutant form results in increased susceptibility to Dextran Sulfate | PMID:30102254 | CNR2 | multiple interactions | ISO | Cnr2 (Mus musculus) | 6480464 | CTD | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CNR2 mRNA; CNR2 gene mutant form promotes the reaction [Dextran Sulfate results in increased secretion of MPO protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; CNR2 protein affects the reaction [Dextran Sulfate results in decreased phosphorylation of MTOR protein]; CNR2 protein affects the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]; CNR2 protein affects the susceptibility to [Azoxymethane co-treated with Dextran Sulfate]; SB 203580 inhibits the reaction [Dextran Sulfate results in increased expression of CNR2 protein] | PMID:27611972 PMID:27920472 PMID:29950665 PMID:30102254 PMID:32942172 | | ||||||||||||||||||||||
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