GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | Chlorpyrifos results in increased expression of BAX mRNA; Chlorpyrifos results in increased expression of BAX protein | PMID:29859868 PMID:30990955 PMID:31823260 PMID:33908150 PMID:34678318 PMID:35439518 | Bax | multiple interactions | EXP | | 6480464 | CTD | 3-(indol-3-yl)propionic acid inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; [Hesperidin co-treated with Chlorpyrifos] results in increased expression of BAX mRNA; acetovanillone analog inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; Berberine inhibits the reaction [Chlorpyrifos results in increased expression of BAX mRNA]; Chlorpyrifos promotes the reaction [STAT1 protein binds to BAX promoter]; Plant Extracts inhibits the reaction [Chlorpyrifos results in increased expression of BAX mRNA]; Plant Extracts inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; Quercetin inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; STAT1 protein affects the reaction [Chlorpyrifos results in increased expression of BAX protein] | PMID:29859868 PMID:30990955 PMID:31823260 PMID:33908150 PMID:34678318 PMID:35439518 | Bax | affects expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Chlorpyrifos affects the expression of BAX protein | PMID:30378422 | Bax | decreases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in decreased expression of BAX protein | PMID:22515965 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in increased expression of BAX mRNA; Chlorpyrifos results in increased expression of BAX protein | PMID:27737797 PMID:32120800 PMID:33349080 PMID:36152060 PMID:36811218 PMID:37019170 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Chlorpyrifos results in increased expression of BAX mRNA | PMID:30981936 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | [Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in decreased expression of BAX protein; ginsenoside Rg1 inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; Ginsenosides inhibits the reaction [Chlorpyrifos results in increased expression of BAX mRNA]; Plant Extracts inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein]; Polyphenols inhibits the reaction [Chlorpyrifos results in increased expression of BAX protein] | PMID:22515965 PMID:32120800 PMID:36152060 PMID:36811218 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX protein | PMID:32800223 | |
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