GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pon2 | decreases expression | ISO | PON2 (Homo sapiens) | 6480464 | CTD | Chlorpyrifos results in decreased expression of PON2 mRNA; Chlorpyrifos results in decreased expression of PON2 protein | PMID:36058312 | Pon2 | decreases expression | ISO | Pon2 (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in decreased expression of PON2 mRNA | PMID:29404631 | Pon2 | increases activity | ISO | PON2 (Homo sapiens) | 6480464 | CTD | Chlorpyrifos results in increased activity of PON2 protein | PMID:24979751 | Pon2 | increases expression | ISO | PON2 (Homo sapiens) | 6480464 | CTD | Chlorpyrifos results in increased expression of PON2 mRNA | PMID:24979751 | Pon2 | multiple interactions | ISO | PON2 (Homo sapiens) | 6480464 | CTD | [APOE protein affects the susceptibility to Chlorpyrifos] which affects the expression of PON2 mRNA; Plicamycin inhibits the reaction [Chlorpyrifos results in increased expression of PON2 mRNA] | PMID:24979751 PMID:29729306 | | ||||||||||||||||||||||
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