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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737416
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2C19
Name: cytochrome P450 family 2 subfamily C member 19
Acc ID: CHEBI:34608
Term: captan
Definition: A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.
Chemical ID: MESH:D002215
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2C19decreases expressionEXP 6480464CTDCaptan results in decreased expression of CYP2C19 proteinPMID:32194361
CYP2C19increases expressionISOCyp2c38 (Mus musculus)6480464CTDCaptan results in increased expression of CYP2C38 mRNAPMID:31558096
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