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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69114
Species: Mus musculus
RGD Object: Gene
Symbol: Pdk4
Name: pyruvate dehydrogenase kinase, isoenzyme 4
Acc ID: CHEBI:34595
Term: Butylbenzyl phthalate
Definition: A benzyl ester that has formula C19H20O4.
Chemical ID: MESH:C027561
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdk4multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of PDK4 mRNAPMID:37364641
Pdk4increases expressionISOPDK4 (Homo sapiens)6480464CTDbutylbenzyl phthalate results in increased expression of PDK4 proteinPMID:31629899
Pdk4multiple interactionsISOPDK4 (Homo sapiens)6480464CTDbutylbenzyl phthalate results in increased expression of and results in increased stability of PDK4 mRNAPMID:31629899
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