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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308374
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sirt3
Name: sirtuin 3
Acc ID: CHEBI:34595
Term: Butylbenzyl phthalate
Definition: A benzyl ester that has formula C19H20O4.
Chemical ID: MESH:C027561
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sirt3decreases expressionISOSIRT3 (Homo sapiens)6480464CTDbutylbenzyl phthalate results in decreased expression of SIRT3 mRNA; butylbenzyl phthalate results in decreased expression of SIRT3 proteinPMID:26520405
Sirt3decreases expressionISOSirt3 (Mus musculus)6480464CTDbutylbenzyl phthalate results in decreased expression of SIRT3 mRNA; butylbenzyl phthalate results in decreased expression of SIRT3 proteinPMID:27923775 PMID:34520170
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