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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10187
Species: Mus musculus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:34581
Term: Bisphenol B
Definition: A bisphenol that has formula C16H18O2.
Chemical ID: MESH:C492482
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ardecreases activityISOAR (Homo sapiens)6480464CTDbisphenol B results in decreased activity of AR proteinPMID:24563381
Arincreases activityISOAR (Homo sapiens)6480464CTDbisphenol B results in increased activity of AR proteinPMID:30951782
Armultiple interactionsISOAR (Homo sapiens)6480464CTDbisphenol B inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; bisphenol B inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; bisphenol B inhibits the reaction [Testosterone binds to and results in increased activity of AR protein]PMID:27561732 PMID:29392883 PMID:30582956
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