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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11055
Species: Mus musculus
RGD Object: Gene
Symbol: Serpine1
Name: serine (or cysteine) peptidase inhibitor, clade E, member 1
Acc ID: CHEBI:34578
Term: Bisphenol A diglycidyl ether
Definition: A diarylmethane that has formula C21H24O4.
Chemical ID: MESH:C019273
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpine1multiple interactionsISOSerpine1 (Rattus norvegicus)6480464CTD2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of and results in increased secretion of SERPINE1 protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [rosiglitazone inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA]]PMID:18278065
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