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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70988
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akap12
Name: A-kinase anchoring protein 12
Acc ID: CHEBI:34575
Term: bisphenol F
Definition: A bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.
Chemical ID: MESH:C008745
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akap12increases expressionISOAKAP12 (Homo sapiens)6480464CTDbisphenol F results in increased expression of AKAP12 proteinPMID:34186270
Akap12increases methylationISOAKAP12 (Homo sapiens)6480464CTDbisphenol F results in increased methylation of AKAP12 genePMID:31601247
Akap12multiple interactionsISOAKAP12 (Homo sapiens)6480464CTD[bisphenol F co-treated with Fulvestrant] results in increased methylation of AKAP12 gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AKAP12 mRNAPMID:28628672 PMID:31601247
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