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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3866
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nkx2-1
Name: NK2 homeobox 1
Acc ID: CHEBI:34575
Term: bisphenol F
Definition: A bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.
Chemical ID: MESH:C008745
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nkx2-1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NKX2-1 mRNAPMID:36041667
Nkx2-1increases expressionISONkx2-1 (Mus musculus)6480464CTDbisphenol F results in increased expression of NKX2-1 mRNAPMID:30951980
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