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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305974
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cers1
Name: ceramide synthase 1
Acc ID: CHEBI:34575
Term: bisphenol F
Definition: A bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.
Chemical ID: MESH:C008745
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cers1affects expressionISOCers1 (Mus musculus)6480464CTDbisphenol F affects the expression of CERS1 mRNAPMID:30951980
Cers1multiple interactionsISOCERS1 (Homo sapiens)6480464CTD[bisphenol F co-treated with Fulvestrant] results in increased methylation of CERS1 genePMID:31601247
Cers1multiple interactionsISOCers1 (Mus musculus)6480464CTD[bisphenol F co-treated with LIF protein] results in increased expression of CERS1 mRNA; [bisphenol F co-treated with Tretinoin] results in decreased expression of CERS1 mRNAPMID:30951980
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