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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730815
Species: Mus musculus
RGD Object: Gene
Symbol: P2rx7
Name: purinergic receptor P2X, ligand-gated ion channel, 7
Acc ID: CHEBI:34565
Term: benzo[b]fluoranthene
Definition: An ortho- and peri-fused polycyclic arene that consists of a benzene ring fused with a acephenanthrylene ring.
Chemical ID: MESH:C006703
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2rx7increases expressionEXP 6480464CTDbenzo(b)fluoranthene results in increased expression of P2RX7 mRNAPMID:26377693
P2rx7multiple interactionsEXP 6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNAPMID:27858113
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