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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345118
Species: Homo sapiens
RGD Object: Gene
Symbol: PARP1
Name: poly(ADP-ribose) polymerase 1
Acc ID: CHEBI:34565
Term: benzo[b]fluoranthene
Definition: An ortho- and peri-fused polycyclic arene that consists of a benzene ring fused with a acephenanthrylene ring.
Chemical ID: MESH:C006703
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PARP1increases cleavageEXP 6480464CTDbenzo(b)fluoranthene results in increased cleavage of PARP1 proteinPMID:21132278
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