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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310640
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fndc1
Name: fibronectin type III domain containing 1
Acc ID: CHEBI:34565
Term: benzo[b]fluoranthene
Definition: An ortho- and peri-fused polycyclic arene that consists of a benzene ring fused with a acephenanthrylene ring.
Chemical ID: MESH:C006703
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fndc1affects expressionISORGD:13216646480464CTDbenzo(b)fluoranthene affects the expression of FNDC1 mRNA

PMID:26377693
Fndc1multiple interactionsISORGD:13216646480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FNDC1 mRNA

PMID:27858113
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.