GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Crh | increases expression | EXP | | 6480464 | CTD | acephate results in increased expression of CRH mRNA | PMID:12039681 | Crh | increases secretion | EXP | | 6480464 | CTD | acephate results in increased secretion of CRH protein | PMID:12039681 | Crh | multiple interactions | EXP | | 6480464 | CTD | acephate promotes the reaction [FOS protein binds to CRH promoter]; Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased expression of CRH mRNA]; gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased secretion of CRH protein]; Propranolol inhibits the reaction [acephate results in increased expression of CRH mRNA]; Propranolol inhibits the reaction [acephate results in increased secretion of CRH protein] | PMID:12039681 | | ||||||||||||||||||||||
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