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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731002
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:34445
Term: 4-tert-Octylphenol
Definition: An alkylbenzene that has formula C14H22O.
Chemical ID: MESH:C105260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3multiple interactionsISOCasp3 (Mus musculus)6480464CTD4-tert-octylphenol results in increased expression of and results in increased activity of CASP3 protein; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of and results in increased activity of CASP3 proteinPMID:29029336
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