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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68556
Species: Homo sapiens
RGD Object: Gene
Symbol: CCND1
Name: cyclin D1
Acc ID: CHEBI:34445
Term: 4-tert-Octylphenol
Definition: An alkylbenzene that has formula C14H22O.
Chemical ID: MESH:C105260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCND1increases expressionEXP 6480464CTD4-tert-octylphenol results in increased expression of CCND1 mRNA; 4-tert-octylphenol results in increased expression of CCND1 proteinPMID:24684733
CCND1multiple interactionsEXP 6480464CTDESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]; fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]PMID:24684733
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