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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:34445
Term: 4-tert-Octylphenol
Definition: An alkylbenzene that has formula C14H22O.
Chemical ID: MESH:C105260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:685566480464CTD4-tert-octylphenol results in increased expression of CCND1 mRNA, 4-tert-octylphenol results in increased expression of CCND1 protein

PMID:24684733
multiple interactionsISORGD:685566480464CTDESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA], fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]

PMID:24684733
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.