GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ar | decreases activity | EXP | | 6480464 | CTD | 4-tert-octylphenol results in decreased activity of AR protein | PMID:18294747 | Ar | decreases expression | EXP | | 6480464 | CTD | 4-tert-octylphenol results in decreased expression of AR protein | PMID:21463676 | Ar | affects binding | ISO | AR (Homo sapiens) | 6480464 | CTD | 4-tert-octylphenol binds to AR protein | PMID:12161000 | Ar | decreases activity | ISO | AR (Homo sapiens) | 6480464 | CTD | 4-tert-octylphenol results in decreased activity of AR protein | PMID:26867867 | Ar | decreases expression | ISO | Ar (Rattus norvegicus) | 6480464 | CTD | 4-tert-octylphenol results in decreased expression of AR mRNA | PMID:10822019 | Ar | multiple interactions | ISO | AR (Homo sapiens) | 6480464 | CTD | 4-tert-octylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Metribolone results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein] | PMID:18324785 PMID:29162470 PMID:33049310 | | ||||||||||||||||||||||
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