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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621400
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:34444
Term: 4-tert-butylphenol
Definition: A member of the class of phenols that is phenol substituted with a tert-butyl group at position 4.
Chemical ID: MESH:C006862
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i3increases activityISONR1I3 (Homo sapiens)6480464CTDbutylphen results in increased activity of NR1I3 proteinPMID:28927721
Nr1i3multiple interactionsISONR1I3 (Homo sapiens)6480464CTDbutylphen binds to and results in decreased activity of NR1I3 protein alternative formPMID:20869355
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