Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1
Acc ID: CHEBI:34444
Term: 4-tert-butylphenol
Definition: A member of the class of phenols that is phenol substituted with a tert-butyl group at position 4.
Chemical ID: MESH:C006862
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1increases activityEXP 6480464CTDbutylphen results in increased activity of ESR1 protein

PMID:18028983
Esr1affects bindingISORGD:7365596480464CTDbutylphen binds to ESR1 protein

PMID:12598185 PMID:19913605
Esr1increases activityISORGD:7365596480464CTDbutylphen results in increased activity of ESR1 protein

PMID:18028983
Go Back to source page   Continue to Ontology report