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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737239
Species: Homo sapiens
RGD Object: Gene
Symbol: FLG
Name: filaggrin
Acc ID: CHEBI:34421
Term: 4-Hydroxybenzophenone
Definition: A benzophenone that has formula C13H10O2.
Chemical ID: MESH:C024292
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FLGaffects response to substanceEXP 6480464CTDFLG gene mutant form affects the susceptibility to 4-hydroxybenzophenonePMID:30245359
FLGmultiple interactionsEXP 6480464CTD[FLG gene mutant form affects the susceptibility to 4-hydroxybenzophenone] which results in decreased secretion of FSHB protein; [FLG gene mutant form affects the susceptibility to 4-hydroxybenzophenone] which results in increased secretion of EstradiolPMID:30245359
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