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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 13994648
Species: Sus scrofa
RGD Object: Gene
Symbol: CTNNB1
Name: catenin beta 1
Acc ID: CHEBI:3441
Term: carvedilol
Definition: A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
Chemical ID: MESH:C043211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTNNB1decreases expressionEXP 6480464CTDCarvedilol results in decreased expression of CTNNB1 mRNAPMID:16824628
CTNNB1increases expressionEXP 6480464CTDCarvedilol results in increased expression of CTNNB1 proteinPMID:16824628
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