GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | decreases expression | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | carvedilol results in decreased expression of TNF mRNA; carvedilol results in decreased expression of TNF protein | PMID:16310260 PMID:20017808 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | carvedilol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; carvedilol inhibits the reaction [TNF protein results in increased expression of MMP2 protein]; carvedilol inhibits the reaction [TNF protein results in increased expression of MMP9 protein] | PMID:15229385 PMID:17964422 | Tnf | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | Carvedilol inhibits the reaction [Arginine results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; Carvedilol inhibits the reaction [Ethanol results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in increased expression of TNF protein] | PMID:22413959 PMID:25245570 PMID:26036690 PMID:32569593 | | ||||||||||||||||||||||
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