GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Edn1 | decreases expression | ISO | Edn1 (Rattus norvegicus) | 6480464 | CTD | carvedilol results in decreased expression of EDN1 mRNA | PMID:18971572 | Edn1 | decreases expression | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | carvedilol results in decreased expression of EDN1 mRNA; carvedilol results in decreased expression of EDN1 protein | PMID:9500873 | Edn1 | decreases secretion | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | carvedilol results in decreased secretion of EDN1 protein | PMID:11078433 | Edn1 | multiple interactions | ISO | Edn1 (Rattus norvegicus) | 6480464 | CTD | carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium] | PMID:14711191 | Edn1 | multiple interactions | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 protein] | PMID:16428915 | |
Go Back to source page | Continue to Ontology report |