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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2147
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:34395
Term: 4-chloro-m-cresol
Definition: A hydroxytoluene that is 3-methylphenol which is substituted by a chlorine at position 4. A ryanodine receptor agonist.
Chemical ID: MESH:C006984
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Araffects activityISOAr (Mus musculus)6480464CTDchlorocresol affects the activity of AR proteinPMID:18294747
Armultiple interactionsISOAR (Homo sapiens)6480464CTDchlorocresol inhibits the reaction [Metribolone results in increased activity of AR protein]PMID:18324785
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