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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736832
Species: Homo sapiens
RGD Object: Gene
Symbol: EGF
Name: epidermal growth factor
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGFmultiple interactionsEXP 6480464CTDbisphenol S inhibits the reaction [EGF protein binds to EGFR protein]; bisphenol S inhibits the reaction [EGF protein results in increased expression of MYC mRNA]; bisphenol S inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]PMID:33605785
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