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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736485
Species: Mus musculus
RGD Object: Gene
Symbol: Sqstm1
Name: sequestosome 1
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sqstm1affects expressionISOSQSTM1 (Homo sapiens)6480464CTDbisphenol S affects the expression of SQSTM1 proteinPMID:31945527
Sqstm1decreases methylationISOSQSTM1 (Homo sapiens)6480464CTDbisphenol S results in decreased methylation of SQSTM1 genePMID:31601247
Sqstm1multiple interactionsISOSqstm1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SQSTM1 mRNAPMID:36041667
Sqstm1multiple interactionsISOSQSTM1 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of SQSTM1 mRNAPMID:28628672
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