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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735879
Species: Mus musculus
RGD Object: Gene
Symbol: Ache
Name: acetylcholinesterase
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acheaffects methylationEXP 6480464CTDbisphenol S affects the methylation of ACHE genePMID:31683443
Achedecreases methylationEXP 6480464CTDbisphenol S results in decreased methylation of ACHE promoterPMID:33297965
Acheincreases methylationEXP 6480464CTDbisphenol S results in increased methylation of ACHE exonPMID:33297965
Acheincreases activityISOACHE (Homo sapiens)6480464CTDbisphenol S results in increased activity of ACHE proteinPMID:29079494
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