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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628869
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itgb5
Name: integrin subunit beta 5
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgb5affects methylationISOItgb5 (Mus musculus)6480464CTDbisphenol S affects the methylation of ITGB5 genePMID:31683443
Itgb5decreases methylationISOItgb5 (Mus musculus)6480464CTDbisphenol S results in decreased methylation of ITGB5 exonPMID:33297965
Itgb5increases expressionISOITGB5 (Homo sapiens)6480464CTDbisphenol S results in increased expression of ITGB5 proteinPMID:34186270
Itgb5increases expressionISOItgb5 (Mus musculus)6480464CTDbisphenol S results in increased expression of ITGB5 mRNAPMID:30951980
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