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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628659
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nrxn1
Name: neurexin 1
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nrxn1affects methylationISONRXN1 (Homo sapiens)6480464CTDbisphenol S affects the methylation of NRXN1 genePMID:31601247
Nrxn1increases expressionISONrxn1 (Mus musculus)6480464CTDbisphenol S results in increased expression of NRXN1 mRNAPMID:30951980
Nrxn1increases methylationISONrxn1 (Mus musculus)6480464CTDbisphenol S results in increased methylation of NRXN1 exonPMID:33297965
Nrxn1multiple interactionsISONRXN1 (Homo sapiens)6480464CTD[bisphenol S co-treated with Fulvestrant] results in decreased methylation of NRXN1 genePMID:31601247
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