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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2326
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpaincreases expressionISOCebpa (Mus musculus)6480464CTDbisphenol S results in increased expression of CEBPA mRNAPMID:30951980 PMID:30959087
Cebpaincreases expressionISOCEBPA (Homo sapiens)6480464CTDbisphenol S results in increased expression of CEBPA mRNAPMID:27003841
Cebpamultiple interactionsISOCebpa (Mus musculus)6480464CTD[bisphenol S co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of CEBPA mRNA; [bisphenol S co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] affects the expression of CEBPA proteinPMID:27273607 PMID:32220626
Cebpamultiple interactionsISOCEBPA (Homo sapiens)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CEBPA mRNA; [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of CEBPA protein; [bisphenol S co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of CEBPA protein; [bisphenol S co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of CEBPA mRNAPMID:33865937 PMID:35736896
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