GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pou5f1 | decreases methylation | EXP | | 6480464 | CTD | bisphenol S results in decreased methylation of POU5F1 promoter | PMID:33297965 | Pou5f1 | increases expression | ISO | POU5F1 (Homo sapiens) | 6480464 | CTD | bisphenol S results in increased expression of POU5F1 mRNA | PMID:36565802 | Pou5f1 | multiple interactions | ISO | POU5F1 (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with perfluorooctanoic acid co-treated with bisphenol S co-treated with perfluorooctane sulfonic acid] results in increased expression of POU5F1 mRNA; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of POU5F1 mRNA | PMID:28628672 PMID:37834465 | |
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