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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318706
Species: Mus musculus
RGD Object: Gene
Symbol: Loxl1
Name: lysyl oxidase-like 1
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Loxl1affects expressionEXP 6480464CTDbisphenol S affects the expression of LOXL1 mRNAPMID:30951980
Loxl1increases methylationEXP 6480464CTDbisphenol S results in increased methylation of LOXL1 exonPMID:33297965
Loxl1multiple interactionsEXP 6480464CTD[bisphenol S co-treated with Tretinoin] results in decreased expression of LOXL1 mRNAPMID:30951980
Loxl1decreases methylationISOLOXL1 (Homo sapiens)6480464CTDbisphenol S results in decreased methylation of LOXL1 genePMID:31601247
Loxl1multiple interactionsISOLOXL1 (Homo sapiens)6480464CTD[bisphenol S co-treated with Fulvestrant] results in decreased methylation of LOXL1 genePMID:31601247
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