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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69483
Species: Homo sapiens
RGD Object: Gene
Symbol: SYCP2
Name: synaptonemal complex protein 2
Acc ID: CHEBI:34342
Term: 3-methylcholanthrene
Definition: A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Chemical ID: MESH:D008748
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SYCP2increases expressionEXP 6480464CTDMethylcholanthrene results in increased expression of SYCP2 mRNAPMID:20348232
SYCP2multiple interactionsEXP 6480464CTDMethylcholanthrene promotes the reaction [AHR protein binds to SYCP2 promoter]PMID:20348232
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