GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcg2 | affects response to substance | ISO | ABCG2 (Homo sapiens) | 6480464 | CTD | ABCG2 5' UTR affects the susceptibility to Methylcholanthrene | PMID:20804740 | Abcg2 | increases expression | ISO | ABCG2 (Homo sapiens) | 6480464 | CTD | Methylcholanthrene results in increased expression of ABCG2; Methylcholanthrene results in increased expression of ABCG2 mRNA; Methylcholanthrene results in increased expression of ABCG2 mRNA alternative form; Methylcholanthrene results in increased expression of ABCG2 protein | PMID:20804740 PMID:23081912 | Abcg2 | multiple interactions | ISO | ABCG2 (Homo sapiens) | 6480464 | CTD | AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR] | PMID:20804740 | |
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