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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316686
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp39a1
Name: cytochrome P450, family 39, subfamily a, polypeptide 1
Acc ID: CHEBI:34310
Term: (24S)-24-hydroxycholesterol
Definition: A 24-hydroxycholesterol that has S configuration at position 24. It is the major metabolic breakdown product of cholesterol in the brain.
Chemical ID: MESH:C044563
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp39a1increases metabolic processingEXP 6480464CTDCYP39A1 protein results in increased metabolism of 24-hydroxycholesterolPMID:10748047
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