Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730831
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP4A11
Name: cytochrome P450 family 4 subfamily A member 11
Acc ID: CHEBI:34306
Term: 20-HETE
Definition: A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 20.
Chemical ID: MESH:C055987
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP4A11increases chemical synthesisEXP 6480464CTDCYP4A11 protein results in increased chemical synthesis of 20-hydroxy-5,8,11,14-eicosatetraenoic acidPMID:30259074
CYP4A11increases secretionEXP 6480464CTDCYP4A11 protein results in increased secretion of 20-hydroxy-5,8,11,14-eicosatetraenoic acidPMID:23747687
CYP4A11multiple interactionsEXP 6480464CTDisoliquiritigenin inhibits the reaction [CYP4A11 protein results in increased secretion of 20-hydroxy-5,8,11,14-eicosatetraenoic acid]PMID:23747687
Go Back to source page   Continue to Ontology report