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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69309
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fabp4
Name: fatty acid binding protein 4
Acc ID: CHEBI:34283
Term: oxybenzone
Definition: A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.
Chemical ID: MESH:C005290
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fabp4multiple interactionsISOFABP4 (Homo sapiens)6480464CTDoxybenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]PMID:32407875 PMID:34864131
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