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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10127
Species: Mus musculus
RGD Object: Gene
Symbol: Ahr
Name: aryl-hydrocarbon receptor
Acc ID: CHEBI:34283
Term: oxybenzone
Definition: A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.
Chemical ID: MESH:C005290
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ahrdecreases expressionISOAhr (Rattus norvegicus)6480464CTDoxybenzone results in decreased expression of AHR mRNAPMID:15458797
Ahrincreases expressionISOAhr (Rattus norvegicus)6480464CTDoxybenzone results in increased expression of AHR proteinPMID:30099065
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